In a stunning turn of events that left fans on edge, the Tennessee Titans triumphed over the Arizona Cardinals with a score of 22-21 on October 5, 2025, overcoming a daunting 10-game losing streak. The game was held in Glendale, Arizona, where quarterback Cam Ward excelled, amassing a career-best 265 passing yards. What made this victory remarkable was the Titans' resilience, as they staged an astonishing fourth-quarter comeback against a Cardinals team plagued by errors.
At one point in the game, the Titans found themselves in a precarious position, trailing by a significant 21-6 with just over twelve minutes left in the fourth quarter. However, they capitalized on two critical mistakes from the Cardinals, turning the tide of the match in their favor.
One of the most striking moments occurred when Cardinals' running back Emari Demercado appeared to seal the game with an impressive 72-yard touchdown. However, just steps away from the end zone, he celebrated prematurely, losing control of the ball; the fumble was ruled out of the back of the end zone. Instead of extending the lead to 28-6, the Titans regained possession at their own 20-yard line.
This crucial turn of events energized the Titans, who then embarked on an impressive 80-yard drive resulting in their first touchdown in eight quarters of play. During this crucial drive, Calvin Ridley caught a significant 47-yard pass, which was capped off by Tony Pollard's short 1-yard touchdown run, closing the gap to 21-12. Despite the missed extra point, the Titans were back in the game.
The Cardinals' troubles continued when Dadrion Taylor-Demerson intercepted a pass from Ward but fumbled the ball immediately afterward. This miscue allowed Titans receiver Tyler Lockett to recover in the end zone, which narrowed the Cardinals’ lead to just 21-19 with 4:51 remaining.
Despite having the opportunity to secure the win, the Cardinals couldn’t convert on offense and ended up punting the ball back to the Titans with just two minutes left on the clock. Ward’s game-winning drive was highlighted by a striking 38-yard connection to Ridley, setting the stage for Joey Slye’s clutch 29-yard field goal.
Calvin Ridley had a standout performance, completing the game with five receptions for a total of 131 yards.
In terms of player statuses, the Titans had wide receiver Calvin Ridley (dealing with knee and elbow issues) and running back Tyjae Spears (recovering from an ankle injury) active for the game, marking Spears' first appearance this season. However, they were without tackle JC Latham (hip), who missed his fourth consecutive game due to injury, and linebacker James Williams, who left the game with a forearm issue in the second quarter.
On the other side, the Cardinals dealt with several absences including cornerback Max Melton (hamstring), offensive lineman Evan Brown (hamstring), and defensive lineman Darius Robinson (pectoral). Additionally, linebacker Cody Simon exited the game in the first half with a knee problem, and tight end Tip Reiman left the action in the third quarter due to an ankle injury and did not return.
Looking ahead, the Titans are set to clash with the Las Vegas Raiders on Sunday, October 12, while the Cardinals will face off against the Indianapolis Colts on the same day.
This thrilling comeback raises questions about the state of both teams—can the Titans build on this momentum, or will the Cardinals regain their footing after such a demoralizing defeat? Share your thoughts below—do you believe the Titans can turn their season around, or is this just a fleeting moment of hope? Let the debate begin!